Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Must Reads by Date

Must reads for theWeek ending June 14, 2015

Chemotherapy in Advanced Squamous NSCLC, Necitumumab as adjuvant to gemcitabine and cisplatin

Progression-free Survival in Stage III or IV Melanoma, With nivolumab alone, ipilimumab alone, or both together

BMI and Tumor Phenotype in CRC, High BMI reduces benefit of MSI-high tumors

Use of Estrogen by Postmenopausal Women, Does it affect incidence of colorectal cancer?

More must reads

Must reads for theWeek ending June 7, 2015

Prognoses in Metastatic Colorectal Cancer, Can primary tumor location predict survival?

LUMA as a Biomarker for Breast Cancer Risk, Body size and physical activity may play a role

Breast Cancer-Related Lymphedema, Is taxane-based chemotherapy causative?

Risks of Second Primary Cancers in BC Survivors, Exploring the roles of race and ethnicity

More must reads

Must reads for theWeek ending May 31, 2015

Predicting Breast Cancer Survival, Brain metastases increase index’s significance

Inflammation and Breast Cancer, C-reactive protein may be prognostic

Off-label Therapy is Common in Breast Cancer, But, is it based on evidence?

Incidence of Lung Cancer in Chinese-Americans, Does immigration status matter?

Cancer Survivors’ Information Needs, What do they want to know, and when?

More must reads

Must reads for theWeek ending May 24, 2015

FDA Approves Colorectal Cancer Test, Use approved for cobas KRAS mutation test

Predicting RCC Recurrence After Nephrectomy, What story do 16 genes tell?

Race and Ethnicity in Breast Cancer Survival, Tumor subtype is also a factor

Predicting Melanoma Survival, SNPs in Notch pathway genes may be key

BMI and Fitness in Breast Cancer, Do obesity and activity affect risk?

More must reads

Must reads for theWeek ending May 17, 2015

Guideline: Radiotherapy in Locally Advanced NSCLC, ASTRO and ASCO release evidence-based recommendations

Revised International Pediatric Non-Hodgkin Lymphoma Staging System, Expert panel publishes evidence-based system

Statins in Hormone-Sensitive Prostate Cancer, Does statin use affect time to progression?

Predicting CLL Prognosis, Can sequencing identify prognostic markers?

More must reads

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