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Risks of Second Primary Cancers in BC Survivors

Exploring the roles of race and ethnicity

Publish date:: June 2, 2015

The risk of a second primary cancer (SPC) among breast cancer (BC) survivors differs by race and ethnicity, according to a retrospective cohort study of 134,868 non-Hispanic White, 17,484 Black, 18,034 Hispanic, and 19,802 Asian-Pacific Islander (API) women with stage I to III BC. Researchers found:

• All women were at increased risk of second primary BC and acute myeloid leukemia (AML), with higher risk among women with more advanced stage BC.

• Black and API women had higher standardized incidence ratios for AML, at 4.86 and 5.00, respectively, which remained elevated in stage I BC.

• Women with a history of invasive BC have increased risk for SPC, especially second primary BC and AML.

Citation: Calip GS, Law EH, Ko NY. Racial and ethnic differences in risk of second primary cancers among breast cancer survivors [Published online ahead of print May 27, 2015]. Breast Cancer Res Treat. doi: 10.1007/s10549-015-3439-7.

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