Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Must Reads by Date

Must reads for theWeek ending June 3, 2018

Head and neck cancer therapy toxicities greater in women, Cristina V et al. JAMA Oncol. 2018 May 24. doi: 10.1001/jamaoncol.2018.1080.

Colorectal cancer costs twice as much in US as Canada, Yezefski et al. ASCO 2018 Abstract LBA3579.

Prostate cancer: Docetaxel prednisone response better in black men, Halabi et al, George et al. ASCO 2018 Abstracts LBA5005 and LBA5009.

Atezolizumab boosts outcomes in squamous NSCLC, Jotte et al. ASCO 2018 Abstract LBA9000.

More must reads

Must reads for theWeek ending June 3, 2018

Head and neck cancer therapy toxicities greater in women, Cristina V et al. JAMA Oncol. 2018 May 24. doi: 10.1001/jamaoncol.2018.1080.

Colorectal cancer costs twice as much in US as Canada, Yezefski et al. ASCO 2018 Abstract LBA3579.

Prostate cancer: Docetaxel prednisone response better in black men, Halabi et al, George et al. ASCO 2018 Abstracts LBA5005 and LBA5009.

Atezolizumab boosts outcomes in squamous NSCLC, Jotte et al. ASCO 2018 Abstract LBA9000.

More must reads

Must reads for theWeek ending May 27, 2018

FDA postmarketing requirements, Nabhan C et al. JAMA Oncol. 2018 May 10. doi:10.1001/jamaoncol.2018.0610.

Upswing in childhood lymphomas, Siegel DA et al. ASPHO 2018, Abstract 605.

Dapagliflozin suppresses hepcidin, Ghanim HA et al. AACE 2018, Abstract 228.

Methotrexate or nelarabine plus chemo in pediatric T-ALL or T-L, Dunsmore KP et al. ASCO 2018, Abstract 10500.

Blood type is diarrhea destiny, Kumar P et al. J Clin Invest. 2018 May 17; doi: 10.1172/JCI97659.

More must reads

Must reads for theWeek ending May 20, 2018

Widespread Zika screens not cost effective, Saá P et al. New Engl J Med. 2018;378:1778-88. doi: 10.1056/NEJMoa1714977

New cancer drugs linked to fewer arrhythmias, Nickel A et al. annual meeting of the American College of Cardiology ACC 18, Abstract #900-06.

Good ALL outcomes in Down syndrome children, Maloney K et al. ASPHO 2018, annual meeting of the American Society of Pediatric Hematology/Oncology Abstract PP 2001

Reducing morbidity in postpartum hemorrhage, Smith R et al. Annual clinical and scientific meeting of the American Society of Obstetricians and Gynecologists 2018, Abstract 26R.

Flat pricing of ibrutinib , Sales revenues at the potential expense of patient safety https://cancerletter.com/articles/20180413_5/

More must reads

Must reads for theWeek ending May 13, 2018

miRNAs are biomarkers for RCC prognosis, Pan X et al. Biomedicine and Pharmacotherapy 102: 2018; 718-27. https://doi.org/10.1016/j.biopha.2018.03.072

Pseudocapsule status predicts RCC prognosis, Xi W et al. The Journal of Urology 199: 2018; 915-20. https://doi.org/10.1016/j.juro.2017.10.043

New model uses histologic subtypes to predict RCC prognosis, Leibovich B et al. European Urology 73; 2018: 772-80. https://doi.org/10.1016/j.eururo.2018.01.005

Histologic similarities in clear cell papillary RCC and tuberous sclerosis, Williamson S et al. Human Pathology 75; 2018: 10-15 https://doi.org/10.1016/j.humpath.2017.11.013

Fertility poor irrespective of conditioning regimen for transplants , Oquendo del Toro H et al. The 2018 Bone Marrow Transplant Tandem Meetings, Abstract 88.

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