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Acceptance and commitment therapy reduced IBD stress, depression
The 8-week mindfulness course improved stress and depression in patients with inflammatory bowel disease.
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Meta-analysis generally supports LI-RADS classification accuracy
But 13% of lesions classified as probably benign (LI-RADS2) were actually hepatocellular carcinomas.
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NASH: Fastest-growing cause of liver cancer in transplant candidates
Its prevalence rose nearly 700% between 2002 and 2017.
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Long-term budesonide oral suspension well tolerated in EoE
In all, 42% of initial responders maintained a histologic response.
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AGA Clinical Practice Update: Functional gastrointestinal symptoms in patients with inflammatory bowel disease
It’s essential to determine whether the symptoms are caused by inflammation or another etiology that can be addressed separately.
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AGA Guideline: Treatment of mild to moderate ulcerative colitis
Mesalamine and diazo-bonded 5-aminosalicylic acid are still the primary drugs recommended for treatment.
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Single-dose tafenoquine appears to prevent malaria relapse
The drug cut relapse rates in select patients without causing symptomatic anemia.
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Anaerobically prepared donor FMT led to steroid-free remission of ulcerative colitis
Eight weeks after FMT, 32% of the donor group achieved steroid-free remission, compared with 9% of the autologous FMT group (odds ratio, 5; P...
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INPULSIS-ON: Nintedanib shows manageable long-term safety for IPF
IFP has had a poor prognosis and long-term data on treatment options are needed.
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Platinum-etoposide, taxanes best for small cell transformed EGFR-mutant lung cancer
Both platinum-etoposide and taxane therapies produced high response rates (71% each), but patients did not respond to checkpoint inhibitor therapy...
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Adding veliparib to doublet therapy for NSCLC gives slight boost in PFS
Median progression-free survival was 6.1 months for veliparib plus cisplatin-etoposide versus 5.5 months for placebo plus cisplatin-etoposide.
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Low-normal thyroid function tied to advanced fibrosis
In all, 5.9% of adults with low-normal thyroid function had advanced liver fibrosis, compared with 2.8% of individuals with strict-normal thyroid...
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Adverse events a potential concern for chemotherapy-nivolumab in advanced gastric cancer
Adverse events led to dose delays or reductions in 95% of patients. Serious adverse events affected 15% of patients and in most cases led them to...
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Plerixafor produced dramatic responses in severe WHIM syndrome
The treatment was effective and well tolerated in patients who could not receive granulocyte colony-stimulating factor therapy.
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CRP predicts anti-TNF response in ankylosing spondylitis
A baseline C-reactive protein level more than three times above the upper limit of normal correlated significantly with 12-week etanercept...