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Western diet linked to lower microbiome diversity
MIAMI – Chief culprits included fried foods, sodas, fatty sweets, processed meats, ready-cooked meals, and desserts. Fresh fruit and fish showed...
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Hyperglycemia drives leaky gut syndrome, inflammation
MIAMI - HbA1c strongly correlated with the influx of microbial molecules in humans. Correcting hyperglycemia prevented enteric infections and...
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Study eyes biomarkers of regorafenib response in hepatocellular carcinoma
Among 266 proteins tested, decreased levels of 5 correlated with significantly longer overall survival on regorafenib therapy.
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Mucosal impedance contour rapidly distinguished GERD, non-GERD, and eosinophilic esophagitis
The device was safe and rapidly distinguished GERD from non-GERD and eosinophilic esophagitis.
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More fiber looks safe, might benefit ICU patients
MIAMI – Each 10-g increase in fiber intake over 72 hours correlated with a 0.3% median increase in the relative abundance of short-chain fatty...
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Proinflammatory microbiome tied to colorectal adenoma
MIAMI – The fecal presence of at least two genotoxic or proinflammatory bacterial genes conferred nearly 200% greater odds of colorectal adenoma (...
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For patients with end-stage liver disease, acute care incurs steep costs
Mean end-of-life costs exceeded those for ischemic heart disease, diabetes, mental health disorders, and congestive heart failure. Only chronic...
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Semaglutide plus SGLT2 inhibitors improves glycemic control in type 2 diabetes
Once-weekly treatment with the GLP-1 RA semaglutide helped most patients with type 2 diabetes on SGLT2 inhibitors meet their glycemic targets and...
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Golimumab plus methotrexate looks good in early psoriatic arthritis
Rates of DAS remission were 81% versus 42% with methotrexate monotherapy.
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One-time, universal hepatitis C testing cost effective, researchers say
Compared with birth cohort screening alone, universal one-time screening for hepatitis C was cost effective as long as the prevalence of chronic...
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Novel capsid assembly modulator shows promise in HBV
However, one patient developed severe rash soon after completing treatment.
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AGA Clinical Practice Update: Changing utility of serology and histologic measures in celiac disease
For children and adolescents with strong clinical suspicion for celiac disease, repeated transglutaminase-2-IgA (TG2-IgA) levels that are more...
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AGA Clinical Practice Update: Surgical risk assessment and perioperative management in cirrhosis
Patients with cirrhosis should be risk stratified and counseled accordingly before all but the most urgent surgeries, cautions a clinical practice...
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Interactive online module improved detection of Barrett’s esophagus neoplasia
Median detection rates for BORN rose by 30% after training.
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Barrett’s esophagus uncommon in patients with uncomplicated GERD
Nearly 14% of esophagogastroduodenoscopies were for GERD without alarm symptoms; 5.6% of these patients had suspected Barrett’s esophagus.