Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Optimal management of Barrett's esophagus without high-grade dysplasia
Key clinical point: In patients with Barrett’s esophagus and low-grade dysplasia confirmed by repeat endoscopy, endoscopic eradication therapy is the optimal cost-effective management strategy. For patients with nondysplastic Barrett’s esophagus, the optimal surveillance interval is every 3 years for men and every 5 years for women.
Major finding: This strategy decreased esophageal adenocarcinoma incidence by 66% and mortality by 81%, compared with natural history.
Study details: A cost-effectiveness analysis using three population-based models.
Disclosures: The National Institutes of Health/National Cancer Institute supported the study and provided funding for the authors.
Omidvari A-H et al. Clin Gastroenterol Hepatol. 2019 Dec 6. doi: 10.1016/j.cgh.2019.11.058.