Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Barrett’s esophagus risk factors vary by patient sex

Key clinical point: In males but not females, hyperinsulinemia, insulin resistance, and metabolic syndrome are independently associated with a higher risk of Barrett’s esophagus.

Major finding: For men with metabolic syndrome, each additional syndrome criterion increased risk of Barrett’s esophagus by 40% (P = .005).

Study details: A population-based case-control study involving 227 cases and 241 controls.

Disclosures: The study was funded by the Queensland Cancer Fund, Queensland Government Smart State Fund, and the Princess Alexandra Hospital Research Foundation, and others. The investigators reported no disclosures.

Citation:

Kendall BJ et al. J Clin Gastroenterol. 2019 Dec 24. doi: 10.1097/MCG.0000000000001307.