Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Barrett’s esophagus risk factors vary by patient sex
Key clinical point: In males but not females, hyperinsulinemia, insulin resistance, and metabolic syndrome are independently associated with a higher risk of Barrett’s esophagus.
Major finding: For men with metabolic syndrome, each additional syndrome criterion increased risk of Barrett’s esophagus by 40% (P = .005).
Study details: A population-based case-control study involving 227 cases and 241 controls.
Disclosures: The study was funded by the Queensland Cancer Fund, Queensland Government Smart State Fund, and the Princess Alexandra Hospital Research Foundation, and others. The investigators reported no disclosures.
Kendall BJ et al. J Clin Gastroenterol. 2019 Dec 24. doi: 10.1097/MCG.0000000000001307.