News
Suicide rate high in patients with head and neck cancer
Key clinical point: Patients with head and neck cancer have a significantly higher suicide rate than the general population. Major finding: The...
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Survivors of childhood cancers at increased risk for autoimmune diseases
Key clinical point: Survivors of childhood cancers, especially leukemia, Hodgkin lymphoma, and renal tumors, had a significantly increased risk of...
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Higher Risk for Basal Cell Carcinoma Linked to Menopausal Hormone Therapy
Key clinical point: Risk of basal cell carcinoma was higher in women with late age of natural menopause and in women who used menopausal hormone...
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Surgery, dose-escalated chemoradiotherapy yield similar outcomes in NSCLC
Key clinical point: After a complex induction protocol, patients with non–small cell lung cancer (NSCLC) who underwent surgery vs. dose-escalated...
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Adjuvant lapatinib added no benefit against head and neck squamous cell carcinoma
Key clinical point: After surgery for high-risk squamous cell carcinoma of the head and neck, the addition of lapatinib to chemoradiotherapy and...
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Higher risk of basal cell carcinoma linked to menopausal hormone therapy
Late age of natural menopause and use of menopausal hormone therapy were associated with significantly increased risk of basal cell carcinoma,...
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Adjuvant imatinib for 3 years better than 1 year in high-risk GIST
Key clinical point: Patients with high-risk GIST treated with adjuvant imatinib for 3 years had longer relapse-free survival (RFS) and overall...
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Dose-intensive, multiagent regimen improves outcomes from low-risk rhabdomyosarcoma
Key clinical point: A dose-intensive, multiagent regimen including dose-compressed cycles of ifosfamide/etoposide and vincristine/doxorubicin/...
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Intermittent interferon falls short for stage III melanoma patients
Key clinical point: Distant metastasis-free survival and overall survival were similar in patients with stage III melanoma treated with...
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Low BMI predicted worse survival in mCRC
Key clinical point: Low BMI predicted worse overall and progression-free survival in patients with mCRC. Major finding: Risks of death and...
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High-radiation doses improve survival with inoperable intrahepatic cholangiocarcinoma
Key clinical point: High-radiation doses delivered to hepatic tumors were well tolerated and survival outcomes were comparable to surgical...
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Gene mutations had little impact on everolimus benefit in advanced breast cancer
Key clinical point: Mutations in genes involved in the PI3K/mTOR pathway, FGFR signaling, and cell cycle regulation had little impact on...
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Blacks receive inferior care for localized prostate cancer
Key clinical point: Compared with whites, black patients with localized prostate cancer received lower quality of care. Major finding: Blacks...
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Small nucleolar RNA signals colorectal cancer outcomes
Expression of small nucleolar RNA SNORA42 was associated with poor overall and disease-free survival in patients with colorectal cancer.
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Cladribine plus cytarabine yields 85% 5-year survival in Langerhans cell histiocytosis
After standard therapy failed, cladribine plus cytarabine was effective in treating patients with high-risk, organ-positive Langerhans cell...