News
Minimally invasive and abdominal hysterectomy yield similar results for endometrial cancer
Key clinical point: Robot-assisted and laparoscopic hysterectomy had long-term survival comparable to that of abdominal hysterectomy in patients...
News
Patient prognostic score may lessen DCIS overtreatment
Key clinical point: A recurrence risk score based on clinicopathologic features of ductal carcinoma in situ (DCIS) was associated with survival...
News
Proton radiotherapy effective for childhood medulloblastoma
Key clinical point: Proton radiotherapy for childhood medulloblastoma resulted in similar survival outcomes to those of photon-based therapy and...
News
Gemtuzumab ozogamicin boosts overall survival in older AML patients
First-line, low-dose gemtuzumab ozogamicin significantly improved overall survival, compared with best supportive care in patients aged 61 years...
News
CAR T-cells induce remissions, avoid GVHD in relapsed B-cell malignancies
Key clinical point: In patients who relapsed after allogeneic hematopoietic stem-cell transplantation, anti-CD19 chimeric antigen receptor (CAR) T...
News
Peripheral T-cell lymphoma incidence and survival varies significantly by race
Key clinical point: Peripheral T-cell lymphoma incidence, proportions of subtypes, and survival differed markedly among racial/ethnic...
News
CD30 identified as novel target in systemic mastocytosis
Key clinical point: In mast cells isolated from patients with systemic mastocytosis, the antibody-conjugate brentuximab-vedotin inhibited growth...
News
Proper hydroxyurea dose tied to better survival in sickle cell anemia
Key clinical point: Proper hydroxyurea dose in adults with sickle cell anemia was linked to higher fetal hemoglobin levels, less organ dysfunction...
News
RCTs vs. observational studies: mortality ‘strikingly’ different following RT
Key clinical point: Analysis of randomized trial data compared with observational data on mortality after breast cancer radiotherapy shows...
News
Significant risk of relapse remains for ER-positive breast cancer patients beyond 10 years
Key clinical point: The risk of breast cancer recurrence continues through 24 years after primary treatments, especially for estrogen receptor–...
News
Death from late effects of childhood cancer on decline
Key clinical point: Five-year survivors of childhood cancers have increased lifespans due in part to reduced rates of treatment-related late...
News
Volasertib active against platinum-resistant, refractory ovarian cancer
Key clinical point: Volasertib showed activity against platinum-resistant or -refractory ovarian cancer; adverse effects were mostly hematologic...
News
Antilymphocyte globulin curbs chronic graft-versus-host disease
Key clinical point: Chronic graft-versus-host disease (GVHD) after allogeneic stem cell transplantation with peripheral blood stem cells was less...
News
Daratumumab clinically active, well tolerated in heavily treated multiple myeloma
Key clinical point: Daratumumab monotherapy was clinically active and well tolerated in patients with multiple myeloma who were treated with at...
News
KIR2DL5B genotype predicts outcome in chronic phase–CML
Key clinical point: The presence of KIR2DL5B was associated with worse outcomes in patients with chronic phase–chronic myeloid leukemia treated...