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WHO recommends pilot projects for malaria vaccine
a malaria-endemic region Photo by Sarah Mattison More testing is needed before the malaria vaccine candidate RTS,S/AS01 (Mosquirix) can be put...
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New melphalan formulation denied approval
Photo by Chad McNeeley The US Food and Drug Administration (FDA) has said that, at present, it cannot approve a propylene glycol-free melphalan...
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Genetic variation influences effect of malaria vaccine candidate
Photo by Caitlin Kleiboer Results of a genomic sequencing analysis appear to explain why the malaria vaccine candidate RTS,S/AS01 (Mosquirix) is...
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Team targets gene to increase RBC production
Researchers say they can increase the production of red blood cells (RBCs) in the lab by targeting a single gene—SH2B3. The team used RNA...
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Novel compound could treat leukemia
A small-molecule compound that has previously shown activity against Ewing sarcoma and prostate cancer may fight leukemia as well, according to...
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Radiation often underused in follicular lymphoma
woman for radiotherapy Photo by Rhoda Baer SAN ANTONIO—A new study indicates that patients with early stage follicular lymphoma (FL) are...
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Radioimmunotherapy shows promise for HL
Results of a small trial suggest the radiolabeled anti-CD25 antibody 90Y-daclizumab can treat certain patients with relapsed/refractory Hodgkin...
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FDA approves factor X concentrate
The US Food and Drug Administration (FDA) has approved a factor X product derived from human plasma (Coagadex) to treat patients with hereditary...
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HSC finding may have range of implications
Image by Matthias Zepper Murine research has provided new insight into the functionality of hematopoietic stem cells (HSCs). Investigators found...
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‘Room for improvement’ in animal research
Photo by Aaron Logan A study of animal-based research published over the last 70 years suggests that scientists could have done more to reduce...
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Antibody can turn AML cells against each other
Image by Joshua Stokes Scientists say they have discovered an antibody that can transform leukemic cells into immune cells that target their...
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Older RBCs don’t increase risks, study suggests
Photo by Elise Amendola Patients undergoing cardiac surgery can safely receive transfusions with older red blood cells (RBCs), according to new...
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Drug-resistant malaria could spread to Africa, team says
of Plasmodium falciparum Image by Mae Melvin/CDC New research indicates that drug-resistant forms of the malaria parasite Plasmodium falciparum...
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NICE plans to recommend device for SCD patients
Image by Graham Beards The UK’s National Institute for Health and Care Excellence (NICE) is asking for views on its plans to recommend a device...
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6PGD inhibitors could treat leukemia, other cancers
Photo by Rhoda Baer Preclinical research suggests that compounds derived from Himalayan rhubarb could potentially treat leukemias and other...