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Findings may help advance treatment of malaria
Researchers have found that a screening model can classify antimalarial drugs and reveal drug targets for Plasmodium falciparum, according to a...
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Team evaluates long-term tolerability of ticagrelor
Photo courtesy of AstraZeneca ORLANDO, FL—A subanalysis of the PEGASUS-TIMI 54 trial has provided a clearer picture of the risks and benefits...
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Pharma companies fail to disclose trial information
Photo by Esther Dyson New research indicates that pharmaceutical companies are still failing to disclose trial information publicly, despite...
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ESRD treatments linked to different cancers
Photo by Anna Frodesiak Patients with end-stage renal disease (ESRD) may have different cancer risks according to the treatment they are...
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Analysis suggests dabigatran is safer than warfarin
ORLANDO, FL—Interim results from a long-term, “real world” study suggest dabigatran etexilate mesylate (Pradaxa) may be safer than warfarin in...
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Antidote reverses effects of apixaban, rivaroxaban in healthy subjects
An investigational antidote to factor Xa inhibitors has proven succesful in reversing the effects of apixaban and rivaroxaban in a pair of phase 3...
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Drug ‘life-changing’ for CLL patients in phase 1 trial
Photo courtesy of NIH A novel Bruton’s tyrosine kinase inhibitor has proven life-changing for patients with chronic lymphocytic leukemia (CLL) who...
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Inhibitor exhibits ‘modest’ activity in lymphoma
A small-molecule inhibitor has shown modest anticancer activity in a phase 1 trial of patients with relapsed/refractory lymphoma or multiple...
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Predicting risk of VTE in patients with leg casts
Photo by Nikki McLeod Researchers say they have developed prediction models and a scoring system that can help identify a high risk of venous...
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Relapses ‘critical’ for sustained malaria transmission
Plasmodium vivax Image by Mae Melvin New research indicates that most childhood malaria infections in Papua New Guinea (PNG) are the result of...
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CCSs have increased risk of autoimmune diseases
Photo by Bill Branson Childhood cancer survivors (CCSs) have an increased risk of developing autoimmune diseases, according to research published...
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Study raises questions about iron dosing
A new study suggests it may be difficult for the body to absorb iron in the necessary or desired quantities when iron supplements are administered...
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Drug protects fertility in chemo-treated mice
Photo courtesy of UW Health The heart medication dexrazoxane can protect fertility and improve survival in female mice receiving the...
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Models predict impact of malaria vaccine candidate
Photo by Caitlin Kleiboer The malaria vaccine candidate RTS,S/AS01 (Mosquirix) could have a significant impact on public health in a range of...
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Team describes new way to edit HSPCs
Image by Tom Ellenberger Researchers say they have discovered a more efficient way to edit the genomes of hematopoietic stem and progenitor cells...