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Liraglutide seems safe, effective in children already on metformin

Publish date:: May 3, 2019

Key clinical point: Liraglutide is safe and effective in children and adolescents with type 2 diabetes who are on metformin.

Major finding: Liraglutide therapy was associated with a significantly greater decrease in mean glycated hemoglobin levels, compared with placebo.

Study details: The phase 3, randomized, placebo-controlled ELLIPSE study in 134 children and adolescents with type 2 diabetes.

Disclosures: Novo Nordisk, which manufactures liraglutide, supported the study. Twelve authors reported grants or support from Novo Nordisk in relation to the trial. Three authors were employees of Novo Nordisk. Eight authors reported unrelated grants and fees from Novo Nordisk and other pharmaceutical companies.

Citation:

Tamborlane WV et al. N Engl J Med. 2019 Apr 28. doi: 10.1056/NEJMoa1903822.

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