Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Must Reads by Date

Must reads for theWeek ending December 27, 2015

The Pathogenesis of Lacunar Stroke, Assessing associations in subtypes

Predicting Progression from MCI to AD, Markers in plasma and CSF hold predictive value

Surgical Exposure and Dementia, Is it a risk factor?

Depression in MS Patients, Evaluating prevalence of therapy

More must reads

Must reads for theWeek ending December 20, 2015

Axonal Loss in Optic Neuritis, Studying damage to the RNFL and GCC

Comorbidities in Myasthenia Gravis, Identifying the most common associations

Rituximab Therapy in MS and NMO, Assessing safety and efficacy over 50 patient years

AQP4 Antibodies in Lupus, Assessing their effect on neuromyelitis optica spectrum disorders

Fingolimod in Multiple Sclerosis, Evaluating changes in lymphocyte subset distribution

More must reads

Must reads for theWeek ending December 13, 2015

Fingolimod as Second-line Therapy in RRMS, Comparing it with a second iDMT

MOG and AQP4 Antibodies in Neuromyelitis Optica, Studying their associations in children

Fingolimod in Relapsing Multiple Sclerosis, Comparing it with placebo

Genetic Factors in Multiple Sclerosis, How do they affect IFNβ response?

Disease-Modifying Drugs in RRMS, Associations with disability progression

More must reads

Must reads for theWeek ending December 6, 2015

MRI Lesion Detection in Multiple Sclerosis, Comparing conventional and “advanced” techniques

IL-17A in Myasthenia Gravis, Studying associations with sex and disease severity

14bp Polymorphism in Multiple Sclerosis, Could it be a risk factor?

B Cells in Relapsing-Remitting Multiple Sclerosis, Revealing their coordination capabilities

Interferon Beta Stimulated Genes in Multiple Sclerosis, Could they be early biomarkers of treatment response?

More must reads

Must reads for theWeek ending November 29, 2015

Pregnancy After NMOSD Onset, Studying risk factors for miscarriage

Brain Aging Toward Dementia, Assessing decline over time

CAG Expansion in Huntington Disease, Measuring its effect on motor, cognitive, and behavioral scores

Intravenous Methylprednisolone in MS and NMO, Evaluating the effects of subsequent courses

Neuromyelitis Optica Diagnostic Criteria, Assessing their clinical utility

More must reads

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