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IBD Linked to Small Bowel Cancer
Clin Gastroenterol Hepatol; 2017 Dec; Bojesen, et al
Crohn’s disease increases the risk of small bowel cancer, according to a recent nationwide analysis. The study, which included the entire population aged ≥16 years from 1978 to 2010, found most patients who had developed inflammatory bowel disease-related small bowel carcinoma (IBD-SBC) had moderate to severe IBD.
- The analysis found 40 cases of IBD-SBC in the population, which included 241,620 person-years of follow-up.
- 23 patients with Crohn’s disease had developed small bowel adenocarcinoma.
- Conversely, the risk of small bowel cancer was not detected among patients with ulcerative colitis.
Citation:
Bojesen RD, Riis LB, Høgdall E, et al. Inflammatory bowel disease and small bowel cancer risk, clinical characteristics, and histopathology: A population-based study. Clin Gastroenterol Hepatol. 2017;15:1900-1907.e2.