Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Endoscopy Methods that Detect Neoplastic Lesions
Am J Gastroenterol; ePub 2017 Nov 14; Iacucci, et al
High-definition white-light endoscopy (HD-WLE) is as good as virtual chromoendoscopy (VCE) and dye spraying chromoendoscopy (DCE) to detect colonic neoplastic lesions, according to a randomized trial that compared all 3 methods to one another. Researchers found:
- 270 patients with long-term colitis were evaluated, divided into 3 groups of 90 patients each to be evaluated with HD-WLE, VCE, and DCE.
- VCE was found to be noninferior to DCE for detecting neoplastic lesions.
- High definition endoscopy, on the other hand, was not inferior to either of the other 2 approaches.
- Among the lesions that were detected, the location in the right colon and the Kudo pit pattern were able to predict neoplastic lesions, with odds ratios of 6.52 and 21.5, respectively.
Iacucci M, Kaplan GG, Panaccione R, et al. A randomized trial comparing high definition colonoscopy alone with high definition dye spraying and electronic virtual chromoendoscopy for detection of colonic neoplastic lesions during IBD surveillance colonoscopy. [Published online ahead of print November 14, 2017]. Am J Gastroenterol. doi:10.1038/ajg.2017.417.
This Week's Must Reads
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Gender Differences in Patients Hospitalized with Cirrhosis, J Clin Gastroenterol; ePub 2019 Feb 22; Rubin, et al
POC Test for Identifying Viraemic HCV Infection, J Hepatol; ePub 2019 Feb 21; Freiman, et al
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Hypercholesterolemia & Statin Exposure in Cirrhosis, Gastroenterology; ePub 2019 Jan 18; Kaplan, et al
Response to UDCA Treatment in PBC Patients, Clin Gastroenterol Hepatol; ePub 2019 Jan 4; Cheung, et al