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Risk of Thrombosis & Mortality in Patients with IBD

Clin Transl Gastroenterol; ePub 2018 Apr 3; Andrade, et al

There is an increase mortality risk in patients with inflammatory bowel disease (IBD) who develop thrombosis, a recent study found. Researchers examined the medical electronic chart of 1,093 IBD patients and actively searched their image exams for words related to thrombosis. They found:

  • 654 Crohn’s disease and 439 colitis patients were included.
  • Thrombosis prevalence was 5.1% and mortality rate was higher in patients who had suffered thrombosis.
  • ~ half of patients developed thrombosis in the outpatient setting, 52% of these had disease activity, 17% had recent hospitalization, and 10% had previous thrombosis.
  • A majority of patients who had thrombosis during hospitalization used heparin prophylaxis.

Citation:

Andrade AR, Barros LL, Azevedo MFC, et al. Risk of thrombosis and mortality in inflammatory bowel disease. [Published online ahead of print April 3, 2018]. Clin Transl Gastroenterol. doi:10.1038/s41424-018-0013-8.