Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Risk of Thrombosis & Mortality in Patients with IBD
Clin Transl Gastroenterol; ePub 2018 Apr 3; Andrade, et al
There is an increase mortality risk in patients with inflammatory bowel disease (IBD) who develop thrombosis, a recent study found. Researchers examined the medical electronic chart of 1,093 IBD patients and actively searched their image exams for words related to thrombosis. They found:
- 654 Crohn’s disease and 439 colitis patients were included.
- Thrombosis prevalence was 5.1% and mortality rate was higher in patients who had suffered thrombosis.
- ~ half of patients developed thrombosis in the outpatient setting, 52% of these had disease activity, 17% had recent hospitalization, and 10% had previous thrombosis.
- A majority of patients who had thrombosis during hospitalization used heparin prophylaxis.
Andrade AR, Barros LL, Azevedo MFC, et al. Risk of thrombosis and mortality in inflammatory bowel disease. [Published online ahead of print April 3, 2018]. Clin Transl Gastroenterol. doi:10.1038/s41424-018-0013-8.
This Week's Must Reads
Must Reads in Crohn’s Disease
Ustekinumab & Health-Related Quality of Life in CD, J Crohns Colitis; ePub 2018 May 3; Sands, et al
Increased Risk of Acute MI and HF with IBD, Clin Gastroenterol Hepatol; ePub 2018 Apr 24; Aniwan, et al
Opioid Use Disorder & IBD Hospitalizations, J Crohns Colitis; ePub 2018 May 7; Cohen-Mekelburg, et al
Clinical Course of IBD with Celiac Disease, J Crohns Colitis; ePub 2018 May 7; Tse, et al
Incidence of Intestinal Infections in IBD, Inflamm Bowel Dis; ePub 2018 May 2; Barber, et al