Key clinical point: The Briganti 2019 nomogram accurately predicted lymph node invasion in adults with high-risk, clinically localized prostate cancer.
Major finding: The area under the curve for the Briganti 2019 was 0.71. At a cutoff of 7%, sensitivity, specificity, and negative predictive values were 94.7%, 32.0%a, and 98.8%, respectively.
Study details: The data come from a review of 278 adults with prostate cancer who underwent radical prostatectomy and extended pelvic lymph node dissection. Patients were rated using the Briganti 2019 nomogram; researchers used the area under the curve of the receiver operating characteristic analysis to quantify accuracy.
Disclosures: The study received no outside funding. The researchers had no financial conflicts to disclose.
Source: Fukagawa E et al. Int J Clin Oncol. 2021 Jun 12. doi: 10.1007/s10147-021-01954-4.