Clinical Edge Journal Scan

Preoperative and postoperative models predict post-resection survival in HCC


 

Key clinical point: Preoperative model for end-stage liver disease (MELD) score, post hepatectomy liver failure score (PHLF), and HCC recurrence were independent predictors of survival for HCC patients with cirrhosis who underwent curative liver resection.

Major finding: The preoperative MELD score and grades A, B, or C of the post hepatectomy liver failure score (PHLF) were significant independent predictors for survival in HCC patients with cirrhosis who underwent curative liver resection, with hazard ratios of 1.37 (MELD), 2.33 (grade A), 3.15 (grade B), 373.41 (grade C). HCC recurrence also was a significant independent predictor of survival (HA 11.67).

Study details: The data come from a review of 120 adults with HCC with cirrhosis who underwent curative resection.

Disclosures: The study received no outside funding. The researchers had no financial conflicts to disclose.

Source: Elshaarawy O et al. World J Gastrointest Oncol. 2021 May 15. doi: 10.4251/wjgo.v13.i5.424.

Recommended Reading

PIVKA-II shows promise as HCC biomarker
Federal Practitioner
Clinical Edge Journal Scan Commentary: HCC June 2021
Federal Practitioner
Radiofrequency and microwave ablation show similar success for HCC
Federal Practitioner
EZ-ALBI score predicts liver function in hepatocellular carcinoma
Federal Practitioner
First-line therapies for advanced HCC show similar results
Federal Practitioner
DEPDC1B gene shows potential as therapeutic target for hepatocellular carcinoma
Federal Practitioner
Child-Pugh score predicts postoperative 90-day mortality for HCC post-resection
Federal Practitioner
Adding degradable starch microspheres to Lipiodol fails to improve post-procedure survival in HCC
Federal Practitioner
Gadoxetate disodium and gadobenate dimeglumine show similar perfusion parameters for HCC
Federal Practitioner
Multiple metastases predict poor prognosis in HCC
Federal Practitioner