Diabetes is linked with adverse cardiovascular outcomes in patients with heart failure with preserved ejection fraction (HFpEF), according to an analysis involving nearly 3,400 individuals. Additionally, the risk of adverse outcomes appears to vary depending on the presence of microvascular complications. Participants were an average 69 years of age with HFpEF. Investigators looked at the impact diabetes and microvascular complications had on hospitalization, hospitalization for heart failure, death, and cardiovascular death. Among the results:

• ~One-third of patients with diabetes had at least 1 microvascular complication.
• Patients with diabetes and microvascular complications were at increased risk to be hospitalized, as well as to be hospitalized for heart failure.
• They also had a higher risk of death and cardiovascular death.
• Patients previously hospitalized for heart failure had a higher likelihood of being rehospitalized for such.