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Zoledronate maintains bone loss after denosumab discontinuation
The results suggest that, after achieving nonosteoporotic BMD with denosumab, a single intravenous infusion of zoledronate given 6 months after...
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International lupus community sets out top barriers to improving lupus outcomes
The consensus report is part of an ongoing process of identifying, prioritizing, and implementing strategies to address the most pressing...
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Machine-learning model predicts anti-TNF nonresponse in RA patients
The model could be used to “help up to 40% of European-descent anti-TNF nonresponders avoid ineffective treatments.”
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Almost half of sudden cardiac deaths linked to prior silent MI
Almost half of individuals who died of sudden cardiac death had a myocardial scar at autopsy, indicating a prior silent MI.
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Hyponatremia is a potential and serious complication of prolonged labor
Women presenting at hospital after attempted home births or after prolonged labor at hospital are at risk.
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Lupus pregnancy outcomes show marked improvement in past 20 years
Pregnancy management and outcomes have improved markedly for women with SLE over the past 2 decades but there’s still progress to be made,...
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More cognitive rigidity found in patients with depression plus fibromyalgia
More attention might need to be paid to the role of chronic pain in the study and treatment of depressed patients, researchers suggest.
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Upadacitinib monotherapy appears promising in RA patients with inadequate methotrexate response
The investigational oral Janus kinase (JAK) inhibitor upadacitinib has shown promise as a monotherapy treatment option for patients with active...
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Flu shot can be given irrespective of the time of last methotrexate dose
New finding stems from post hoc analysis of a randomized, controlled trial.
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TNF inhibitor prices rose despite increased drug class competition
Estimated treatments costs for etanercept, infliximab, and adalimumab would have been 40%-45% lower without new competition, a new analysis finds...
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List of medications linked to drug-induced lupus expands
A new data-mining study adds 42 new drugs.
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Criteria-based fibromyalgia diagnosis and rheumatologists’ clinical diagnosis often disagree
New research reveals considerable disparity between rheumatologists’ clinical diagnosis of fibromyalgia and fibromyalgia criteria based diagnosis...
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Compounded pain creams no better than placebo creams in localized chronic pain
At 1 month, creams specifically formulated for neuropathic, nociceptive, or mixed pain had no effect beyond placebo.
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Topical retinoid found effective as microneedling for acne scars
Tazarotene gel 0.1% could be an effective and practical home-based treatment of atrophic postacne scarring.
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Symptomatic hyperuricemia may respond to urate-lowering therapy
Small case-control study serves as “potential rationale” for reclassifying the ACR/EULAR 2015 gout classification criteria, researchers said.