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Most in-hospital pneumonia deaths may not be preventable
Adults who are hospitalized with community-acquired pneumonia (CAP) are at high-risk for short-term mortality.
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Predictors for worse outcomes in low–disease activity RA remain tough to come by
Functional impairment at baseline helps in prediction, but serum biomarkers don’t.
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Prognostic model has clinical utility in mCRPC
The 11-variable model showed significant separation between low-risk and high-risk patients, providing useful guidance in determining...
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Difficult-to-treat RA remains difficult to define
An online survey of rheumatologists revealed a wide variation in views.
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Childhood-onset SLE has major impact in adult life
Study highlights the need for preventive screening measures to be put in place before the age of 30.
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Eosinophils could be a marker for nonceliac gluten or wheat sensitivity
NCGWS could be considered an inflammatory condition of the entire intestinal track and the eosinophil infiltration “may represent a key candidate...
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Study supports effects of smoking, drinking on SLE risk in black women
Small numbers of confirmed SLE cases in a cohort from the Black Women’s Health Study limited the study’s statistical power.
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Real-world bleeding risk with ibrutinib
The Bruton tyrosine kinase inhibitor ibrutinib has been linked to a 20-fold increased risk of major bleeding in blood cancer patients taking...
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Prolonged antimalarial therapy linked to elevated cardiac biomarkers, cardiomyopathy
“The majority of patients with SLE should be considered at risk because most of them receive long-term maintenance therapy.”
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Caution urged over real-world bleeding risk with ibrutinib
Ibrutinib was linked to an almost 20-fold increased risk of major bleeding in blood cancer patients taking concomitant antiplatelet and...
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VEGF inhibitor shows promise in platinum resistant/refractory ovarian cancer
Combining the vascular endothelial growth factor (VEGF) receptor–targeting tyrosine kinase inhibitor apatinib with oral etoposide in people with...
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AS inflammatory back pain criteria fall short in PsA
The presence or absence of back pain in patients with axial radiologic involvement did not affect prognosis, suggesting the value of considering...
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Data support universal adoption of neuroimaging in early-life epilepsy
Yield is deemed “substantially high,” even among children at lowest risk.
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Low disease activity in SLE compares favorably with clinical remission as an acceptable goal
Study looked at 10-year outcomes in sustained clinical remission or low disease activity after disease inception.