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Which Children Fail to Respond to MRSA Treatment?

Pediatrics; ePub 2017 Jun 1; Hamdy, et al

Publish date:: June 23, 2017

Nearly a third of children with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia fail to respond to treatment, according to multicenter retrospective study of children 18 years of age or younger. Details of the study include the following:

There were 232 reported cases of MRSA in the studied cohort, 72 of which failed to respond to treatment (31%).
Among the 232 patients, 23% developed complications and 5 died within 30 days.
Among 174 children who received vancomycin, catheter-related infections were linked to lower odds of failed treatment.
The same analysis found endovascular infections were associated with a greater likelihood of treatment failure.

Citation:

Hamdy RF, Hsu AJ, Stockmann C, et al. Epidemiology of methicillin-resistant Staphylococcus aureus bacteremia in children. [Published online ahead of print June 1, 2017]. Pediatrics. doi:10.1542/peds.2017-0183.

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