Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Maintaining Vitamin D Levels May Reduce Stroke Risk
J Stroke Cerebrovasc Dis; ePub 2017 Jul 11; Li, et al
Maintaining ideal serum 25(OH)D levels may reduce the risk of stroke among US adults, particularly in adult women age <50 years, according to a recent study’s findings, which add to the existing evidence. Data of 13,642 adults aged ≥20 years who participated in the 2001-2006 National Health and Nutrition Examination Survey were analyzed in this study. Serum 25(OH)D was used to reflect vitamin D status. Stroke history was self-reported using questionnaires. Researchers found:
- After adjusting for demographic and lifestyle covariates, vitamin D deficiency [defined as serum 25(OH)D < 12 ng/mL] was significantly associated with increased risk of stroke, and higher vitamin D levels were significantly associated with reduced risk of stroke.
- The association between high levels of serum 25(OH)D and stroke was particularly evident among young females (aged ≤20 to <50 years).
Li J, Lai H, Yang L, Zhu H, Chen S, Lai S. Age and gender differences in the association between serum 25-hydroxyvitamin D and stroke in the general US population: The National Health and Nutrition Examination Survey, 2001-2006. [Published online ahead of print July 11, 2017]. J Stroke Cerebrovasc Dis. doi:10.1016/j.jstrokecerebrovasdis.2017.05.045.