Clinical Edge

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Meta-analysis: For large proximal polyps, clipping prevents bleeding

Key clinical point: Prophylactically clipping large proximal colorectal lesions after resection may reduce risk of postpolypectomy bleeding.

Major finding: Prophylactically clipping large proximal lesions reduced risk of postpolypectomy bleeding by 63% (relative risk, 0.37; 95% CI, 0.22-0.61; P = .021).

Study details: A meta-analysis including nine randomized controlled trials and 7,197 colorectal lesions.

Disclosures: The investigators reported no external funding or conflicts of interest.

Citation:

Spadaccini M et al. Gastroenterology. 2020 Apr 1. doi: 10.1053/j.gastro.2020.03.051.