Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Impact of Economic Factors on Rectal Cancer Treatment

Ann Surg Oncol; 2017 Feb 24; Lee, Teng, et al

Racial and socioeconomic disparities were seen in adolescents and young adults treated for rectal cancer in a study involving nearly 3,300 individuals.

Participants had clinical stage II-III rectal cancer. Investigators looked at factors linked with receiving adjuvant and surgical therapies, as well as overall survival. Among the results:

  • ~One fourth of black and Hispanic patients did not receive radiation, compared with 17% of whites.
  • ~2 in every 10 black and Hispanic patients did not receive surgery, vs 12% of whites.
  • ~23% of black and Hispanics did not receive chemotherapy, vs 15% of whites.
  • After controlling for competing factors, blacks were 30% less likely to receive neoadjuvant chemoradiation vs whites; Hispanics were 40% less likely to receive such.
  • Those with government insurance were very likely to not receive surgery.
  • After multivariate analysis, race did not impact mortality.
  • Not having surgery had the greatest influence on mortality.

Citation:

Lee D, Teng A, Pedersen R, et al. Racial and socioeconomic treatment disparities in adolescents and young adults with Stage II-III rectal cancer. Ann Surg Oncol. 2017;24(2):311-318. doi:10.1245/s10434-016-5626-0.