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Citrus Consumption in Melanoma

Does it increase risk?

Publish date:: July 7, 2015

Citrus consumption was associated with an increased risk of malignant melanoma, according to studies of 63,810 women and 41,622 men. Researchers followed the 2 cohorts for 24 and 26 years, respectively, and found:

Incident melanomas occurred in 1,840 people.
After adjusting for other risk factors, hazard ratios for melanoma were:
- 1.00 for twice per week citrus consumption (reference)
- 1.10 for 2 to 4 times per week
- 1.26 for 5 to 6 times per week
- 1.27 for 1 to 1.5 times per day
- 1.36 for ≥ 1.6 times per day
Grapefruit showed a hazard ratio of 1.41 associated with consumption ≥ 3 times per week vs never.

Citation: Wu S, Han J, Feskanich D, et al. Citrus consumption and risk of cutaneous malignant melanoma. [Published online ahead of print June 29, 2015]. J Clin Oncol. doi: 10.1200/JCO.2014.57.4111.

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