Bleeding Disorders
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Thrombocytopenia signals multiorgan system failure in acute liver failure
Key clinical point: In patients with acute liver failure (ALF), decreasing platelet counts were associated with systemic inflammation and greater...
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Caplacizumab induces rapid resolution of acute TTP
Caplacizumab induces faster resolution of acute episodes of acquired thrombotic thrombocytopenic purpura than does conventional therapy by...
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Defibrotide offers benefit for severe veno-occlusive disease and multiorgan failure
Key clinical point: Defibrotide improved survival at 100 days after hematopoietic stem cell transplantation (HSCT) in patients with hepatic veno-...
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FDA approves first recombinant von Willebrand treatment
Conference Coverage
Video: Eltrombopag boosted standard therapy in severe, newly-diagnosed aplastic anemia
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VIDEO: ASH highlights five Choosing Wisely initiatives
Conference Coverage
ASH: Genes affecting risk, severity of chronic ITP are identified
Key clinical point: IFNA17 and IFNLR1 may be important candidate genes involved in immune regulation and sustained autoimmunity in immune...
Conference Coverage
Lusutrombopag is effective for thrombocytopenia in liver disease
Key clinical point: In a phase III trial, lusutrombopag was found to reduce the need for platelet transfusion in chronic liver disease patients...
News
FDA approves new treatment for Factor X deficiency
The Food and Drug Administration has provided its first approval of a coagulation factor replacement drug specifically for patients with...
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FDA expands Promacta approval to include pediatric patients
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Novel triple therapy in ITP provides enduring responses
A novel combination of dexamethasone, cyclosporine, and rituximab was well tolerated in patients with chronic ITP, and significantly increased...