Bleeding Disorders
News
Sickle cell trait raises exertional rhabdomyolysis risk
Among blacks soldiers, sickle cell trait doesn’t raise the risk of death but does raise the risk of exertional rhabdomyolysis.
Conference Coverage
Children under 6 with factor XIII deficiency had no major bleeds with recombinant product
Key clinical point: A recombinant form of factor XIII was effective at preventing serious bleeding episodes in young children with factor XIII-A...
Conference Coverage
Hemophilia guideline recommends integrated care model
Key clinical point: An integrated care model is recommended as optimal for management of persons with hemophilia. Major finding: The joint...
News
Hemophilia drugs top Medicaid spending per prescription
Medicaid’s three most expensive drugs by spending per prescription were for treatment of hemophilia, with the cost leader coming in at almost $59,...
News
The liver drives RBC elimination, iron recycling
News
COMP recommends orphan status for drug to treat PNH
The European Medicines Agency’s Committee for Orphan Medicinal Products (COMP) has issued a positive opinion recommending orphan designation for...
News
Mechanism proposed for microvascular thrombosis in thrombotic thrombocytopenic purpura
Key clinical point: In patients with acquired autoimmune thrombotic thrombocytopenic purpura, elevated plasma levels of human neutrophil proteins...
News
Dematin key to erythrocyte membrane stability in mice
Key clinical point: Dematin is newly recognized as a protein crucial to the integrity of red blood cell membranes. Major finding: Dematin’s...
Conference Coverage
Genetic therapy lowers joint bleeding in hemophilia B
COPENHAGEN – It’s early days yet, but results look highly promising for the ability of an experimental gene-transfer therapy to improve...
Conference Coverage
Novel anticoagulants linked to lower intracranial hemorrhages, higher GI bleeds
A real-life comparison of major bleeding risk with anticoagulants showed that in-hospital mortality was lower with novel oral agents than with...
Conference Coverage
Inherited thrombocytopenia type is a risk factor for hematologic cancers
ETV6-related thrombocytopenia (EV6-RT) appears to predispose carriers to acute lymphoblastic leukemia and other hematologic cancers.