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Ulcerative Colitis, Crohn’s Don’t Impact Birth Outcomes

Am J Gastroenterol; 2017 Nov; Martin, et al

Publish date:: November 30, 2017

Neither ulcerative colitis (UC) nor Crohn’s disease (CD) affect a man’s paternity rate or the birth outcomes of his female partner, according to an analysis of the Utah Population Database. Among the findings:

UC and CD affect about 350,000 men of reproductive age.
The Utah Population Database includes 1,245 male patients with CD and 1,368 with UC, who were compared to their male siblings as controls.
66% of UC patients with at least 1 brother had offspring, compared to 61% in the siblings (P= 0.16)
Birth outcomes did not differ either, e.g., the rate of congenital malformations was the same in both groups.
Among CD patients with a least 1 brother, 58% had offspring, vs 57% in controls.

Citation:

Martin L, Peche W, Peterson K, et al. Population based paternity rate and partner birth outcomes among Utah men with inflammatory bowel disease. Am J Gastroenterol. 2017;112:1722-1727. doi:10.1038/ajg.2017.279

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