Cardiology
Q&A
Digoxin increases mortality among women with congestive heart failure
BACKGROUND: Is there a difference in the effect of digoxin for heart failure between women and men? This study is a subgroup analysis of the...
Q&A
HRT and vitamins C and E do not improve coronary disease in women
BACKGROUND: Are HRT and antioxidant vitamins useful for the secondary prevention of coronary events in postmenopausal women?
Q&A
Warfarin plus aspirin more effective than aspirin alone for secondary prevention of MI
BACKGROUND: Is warfarin plus aspirin or high-dose warfarin more effective than aspirin alone to prevent a second heart attack?
Q&A
Should patients with coronary disease and high homocysteine take folic acid?
BACKGROUND: Should patients with coronary artery disease and high homocysteine levels take folic acid? Plasma homocysteine levels predict outcome...
Q&A
Early invasive strategy for acute cardiac ischemia is cost effective
BACKGROUND: Is an early invasive strategy (routine catheterization or revascularization) cost effective in the treatment of unstable angina and...
Q&A
Revascularization not superior to conservative treatment of acute coronary syndromes
Fox KA, Poole-Wilson PA, Henderson RA, et al. Interventional versus conservative treatment for patients with unstable angina or non-ST-elevation...
Clinical Inquiries
In patients with a previous CVA, do antioxidants protect against subsequent stroke?
EVIDENCE-BASED ANSWER: Most recent randomized controlled clinical trials have not found a benefit in antioxidants (vitamin C, vitamin E, and/or...
Clinical Inquiries
Do antioxidants (vitamins C, E) improve outcomes in patients with coronary artery disease?
EVIDENCE-BASED ANSWER: Antioxidant supplements of vitamins E and C do not reduce cardiovascular death in people with coronary artery disease....
Q&A
Duplex ultrasound and Magnetic Responce Angiography are sensitive for severe carotid stenosis
Nederkoorn PJ, Mali WP, Eikelboom BC, et al. Preoperative diagnosis of carotid artery stenosis: accuracy of noninvasive testing. Stroke 2002; 33:...
Q&A
β-blockers no better than placebo in the treatment of vasovagal syncope
Flevari P, Livanis EG, Theodorakis GN, Zarvalis E, Mesiskli T, Kremastinos DT. Vasovagal syncope: a prospective, randomized, crossover evaluation...
Clinical Inquiries
What is the target for low-density lipoprotein cholesterol in patients with heart disease?
EVIDENCE-BASED ANSWER: Large published randomized controlled trials (RCTs) show that pravastatin and simvastatin are well-tolerated and reduce...