Cardiology
Clinical Inquiries
Does warfarin prevent deep venous thrombosis in high-risk patients?
EVIDENCE-BASED ANSWER: Warfarin (Coumadin) is effective in preventing deep venous thrombosis (DVT) among patients with a history of DVT....
Clinical Inquiries
When should we treat isolated high triglycerides?
EVIDENCE-BASED ANSWER: No evidence exists that treating isolated high triglyceride levels in the absence of other risk factors prevents coronary...
Clinical Inquiries
Is combining ACE inhibitors and ARBs helpful or harmful?
EVIDENCE-BASED ANSWER: The combination of angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) has been studied...
Clinical Inquiries
Does lowering diastolic BP to less than 90 mm Hg decrease cardiovascular risk?
EVIDENCE-BASED ANSWER: Although lowering diastolic blood pressure (DBP) is associated with reduced cardiovascular events, systolic blood pressure...
Clinical Inquiries
Which healthy adults should take aspirin?
EVIDENCE-BASED ANSWER: In adults with no history of cardiovascular disease, aspirin reduces the risk of nonfatal myocardial infarction (MI)....
Q&A
Treatment of high LDL saves lives of those with diabetes or cardiovascular disease
BACKGROUND: It is recommended that patients with diabetes mellitus but without symptomatic cardiovascular disease should receive lipid-lowering...
Q&A
Candesartan reduces cardiovascular death in CHF patients on ACE inhibitor
BACKGROUND: Despite high doses of an ACE inhibitor, some angiotensin II is still produced by the kidney. ARB treatment, in addition to an ACE...
Q&A
Antidepressant treatment reduces poststroke mortality
BACKGROUND: Depression commonly occurs after an acute stroke and is associated with an increased risk of poststroke mortality.
Clinical Inquiries
Is folate supplementation indicated for patients with CAD?
EVIDENCE-BASED ANSWER: There is insufficient evidence to advocate the routine use of folate supplementation for the treatment of coronary artery...
Clinical Inquiries
Do ACE inhibitors prevent nephropathy in type 2 diabetes without proteinuria?
EVIDENCE-BASED ANSWER: Angiotensin-converting enzyme (ACE) inhibitors make a significant difference for patients with diabetes as a whole. If...
Clinical Inquiries
How accurate is stress radionuclide imaging for diagnosis of CAD?
EVIDENCE-BASED ANSWER: Stress radionuclide testing is a moderately accurate test compared with coronary angiography for the diagnosis of coronary...