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Allergen Identification Improves AD Outcomes
Int J Dermatol; ePub 2017 Jun 20; Will, et al
Knowledge of identified specific antigens can guide patients to make lifestyle modifications that may improve disease outcomes in atopic dermatitis (AD), a recent study found. Immunoglobulin E (IgE) quantitative assaying of allergens (IgEQAA) and avoidance of allergens may help some patients with AD. IgEQAA has long been implemented by allergists in determining patients’ reactivities for allergic rhinitis and asthma, 2 of the 3 diagnoses in atopic syndrome. In this study, the affected body surface area (BSA) at first presentation, IgEQAA classes, and total IgE concentration were taken retrospectively for 54 patients with AD. Researchers found:
- Of the 54 patients observed, 41 had an abnormally high total IgE concentration (76%).
- Additionally, it was observed that 9 (17%) patients significantly improved after making lifestyle changes.
Will BM, Severino R, Johnson DW. Identification of allergens by IgE-specific testing improves outcomes in atopic dermatitis. [Published online ahead of print June 20, 2017]. Int J Dermatol. doi:10.1111/ijd.13673.