News
Younger children can safely visit HSCT recipients (sometimes)
Children under 12 are welcome – with suitable precautions – to visit patients at some transplant centers, but personae non grata at others.
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No reduction in oral mucositis with folinic acid post transplant
ORLANDO – Folinic acid, a.k.a. leucovorin, offered no benefit for reducing methotrexate-induced oral mucositis in patients receiving GVHD...
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Adrenal-permissive genotype linked to poor prognosis in prostate cancer
Men with an adrenal-permissive allele of the gene HSD3B1 are at high risk for worse outcomes from advanced prostate cancer.
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Survival for older AML patients better with HSCT from unrelated donors
“Our findings lend support to our hypothesis that a young [matched unrelated donor] should be the donor of choice when available,” reported the...
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Global project reveals cancer’s genomic playbook
The Pan-Cancer Analysis of Whole Genomes, an international collaboration, reveals the complexity of oncogenesis.
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Lenvatinib/pembrolizumab has good activity in advanced RCC, other solid tumors
Two-thirds of patients with advanced renal cell carcinoma had a clinical response to the TKI/immune checkpoint inhibitor combination.
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High-dose chemo offers survival benefit only for highest-risk breast cancer
Women with 10 or more involved axilliary nodes or triple-negative breast cancer had a 20-year overall survival benefit from high-dose chemotherapy...
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Echoes of SARS mark 2019 novel coronavirus outbreak
One-third of patients hospitalized for 2019 novel coronavirus infection required ICU admission, and six of the 41 (15%) died.
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Adding cannabinoids to opioids doesn’t improve cancer pain control
A systematic review and meta-analysis found no advantage of adjuvant cannabinoids for control of advanced cancer pain.
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Promising early efficacy of venetoclax/navitoclax in r/r acute lymphoblastic leukemia
ORLANDO – Combining the BCL-2 inhibitor venetoclax with low-dose navitoclax produced good response rates in heavily pretreated patients with B-...
