News
NRAS mutations predict immunotherapy outcomes in melanoma patients
Key clinical point: Patients with advanced melanoma and mutations in the NRAS gene had better responses to immunotherapy than did those without...
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Liquid biopsy consistent with tumor biopsy for NSCLC
Key clinical point: The EGFR mutation L858R detected in both tissue and cfDNA predicted shorter OS and PFS than did the exon 19 deletion. Major...
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Oral Bisphosphonates Linked with Lower Risk of Endometrial Cancer
Key clinical point: Oral bisphosphonate use was modestly associated with reduced risk of endometrial cancer. Major finding: Risk of endometrial...
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Oral bisphosphonates linked with lower risk of endometrial cancer
Key clinical point: Oral bisphosphonate use was modestly associated with reduced risk of endometrial cancer. Major finding: Risk of endometrial...
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Bevacizumab fails to improve outcomes for metastatic uterine leiomyosarcoma
Key clinical point: Bevacizumab added to gemcitabine-docetaxel did not improve outcomes in patients with uterine leiomyosarcoma. Major finding:...
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Uterine cancer low in myomectomy with power morcellation
Key clinical point: Among women who underwent myomectomy, the prevalence of cancers was low but increased with age. Major finding: Rates of...
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Bevacizumab plus ET failed to improve PFS in HER2-negative, HR-positive BC
Key clinical point: In women with HER2-negative, hormone receptor–positive breast cancer, the addition of bevacizumab to endocrine therapy did not...
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Time and money spent locating unknown primary tumor site might be better spent on genomic analyses
Key clinical point: The resources and time spent to locate the primary tumor site in patients with metastatic unknown primary cancer might be...
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Overall survival plateaus at 3 years for ipilimumab-treated melanoma patients
Key clinical point: Ipilimumab-treated advanced melanoma patients alive at 3 years tend to have good long-term outcomes. Major finding: Around...