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Advanced NSCLC responds to nivolumab
Key clinical point: Nivolumab monotherapy for advanced, heavily pretreated non–small cell lung cancer (NSCLC) generated outcomes that surpassed...
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ABVD and Stanford V similar for bulky mediastinal Hodgkin’s lymphoma
Key clinical point: No significant differences in outcomes were observed after treatment with ABVD vs. Stanford V in patients with stage I or II...
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Chemotherapy and stem-cell transplantation combination appears safe
Key clinical point: In Jehovah’s Witness patients with relapsed lymphoma or multiple myeloma, high-dose chemotherapy (HDC) followed by autologous...
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Chronic lymphocytic leukemia prognosis relatively good after transplantation failure
Key clinical point: The prognosis for patients with chronic lymphocytic* leukemia who have undergone failed stem cell transplantation (SCT) is...
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Cixutumumab provided no boost to androgen deprivation therapy
Key clinical point: Cixutumumab added to androgen deprivation (AD) therapy did not improve undetectable PSA rate in men with hormone-sensitive...
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Nivolumab benefits patients with previously treated renal cell carcinoma
Key clinical point: A majority of previously treated patients with renal cell carcinoma benefited from nivolumab. Major finding: At a median 45-...
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Circulating tumor cells and LDH level provide surrogate for survival in advanced prostate cancer
Key clinical point: A biomarker panel of circulating tumor cell count and lactate dehydrogenase level provided a surrogate measure for overall...
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Blood urea nitrogen level and Khorana score predict early pancreatic cancer mortality
Key clinical point: High Khorana score and elevated blood urea nitrogen predicted early mortality in patients after surgical resection for...
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C-reactive protein signals melanoma progression
Key clinical point: In patients with melanoma at any stage, elevated C-reactive protein (CRP) was associated with poorer survival. Major finding:...
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HSCT recipients face increased fracture risk
Key clinical point: Patients who underwent hematopoietic stem-cell transplantation were significantly more likely to develop a fracture compared...
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Lapatinib inferior to trastuzumab for HER2-positive breast cancer
Key clinical point: Lapatinib is inferior to trastuzumab for treating patients with advanced HER2-positive breast cancer. Major finding: The...
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Perioperative treatment with diuretic linked with lower lung cancer recurrence
Key clinical point: After surgical removal of tumors, lung cancer patients treated with atrial natriuretic peptide had a significantly lower...
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Similar outcomes from HSCT found with sibling and unrelated donors
Key clinical point: Children with high-risk acute lymphoblastic leukemia who received stem cell transplants from matched sibling vs.
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MGUS awareness linked to better survival in patients with multiple myeloma
Key clinical point: Patients with multiple myeloma who had prior knowledge of monoclonal gammopathy of undetermined significance (MGUS) survived...
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ACS NSQIP hospitals steadily improve surgical outcomes
Key clinical point: As length of hospital participation in ACS NSQIP increased, the ratio of observed/expected surgery-related adverse events...