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Adjuvant oxaliplatin boosts colon cancer survival
After curative-intent surgery, patients with stage III colon cancer who received oxaliplatin plus capecitabine had improved survival, compared...
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Regorafenib provides low value in metastatic colorectal cancer
Key clinical point: For treatment-refractory metastatic colorectal cancer, regorafenib provides low value at its current cost. Major finding:...
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Outcomes worse with secondary and therapy-related AML compared with de novo AML
Key clinical point: Younger patients with secondary and therapy-related acute myeloid leukemia (sAML and tAML, respectively) have worse outcomes...
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Persistent HPV16 DNA in oral rinse signaled oropharyngeal cancer’s return
Persistent human papillomavirus type 16 (HPV16) DNA detected in posttreatment oral rinses, although infrequent, was associated with HPV-related...
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Similar outcomes for salvage vs. planned surgery after chemoradiotherapy in esophageal cancer
Key clinical point: As management for esophageal cancer, salvage esophagectomy after definitive chemoradiotherapy (SALV) produced similar outcomes...
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Hereditary cancer syndromes highly prevalent in young adults with colorectal cancer
Key clinical point: Patients age 35 years and younger who have colorectal cancer have a high frequency of hereditary cancer syndromes.
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Pomalidomide increases overall survival in multiple myeloma
Key clinical point: In patients with multiple myeloma, both continuous and intermittent dosing regimens of pomalidomide had similar favorable...
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Doxorubicin, radiation doses predict heart risk in lymphoma survivors
Key clinical point: Lymphoma survivors treated with autologous hematopoietic stem-cell transplantation (auto-HSC) had a significantly higher risk...
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Gene expression profiles help identify metastasis in primary cutaneous melanoma
Key clinical point: Molecular data combined with clinicopathologic variables better discriminated between primary cutaneous melanomas that had or...
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Adolescent cancer survivors report more emotional, neurocognitive impairment than do siblings
Key clinical point: Adult cancer survivors diagnosed between ages 11 and 21 years self-reported higher rates of emotional distress and...
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Interim PET provides limited prognostic value for diffuse large B-cell lymphoma
Key clinical point: After two cycles of standardized, dose-dense chemotherapy in patients with diffuse large B-cell lymphoma (DLBCL), positive...
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Consolidation chemotherapy after concurrent chemoradiation failed to improve outcomes in NSCLC
Key clinical point: Docetaxel and cisplatin consolidation chemotherapy (CC) after concurrent chemoradiation failed to prolong progression-free...
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CRd is well tolerated and effective in newly diagnosed and smoldering multiple myeloma
Key clinical point: Patients with newly diagnosed multiple myeloma or smoldering multiple myeloma had high rates of minimal residual disease...
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Urea cream bests antioxidant ointment to prevent chemo-induced hand-foot syndrome
Key clinical point: Urea cream was superior to Mapisal, an antioxidant-containing ointment, in preventing hand-foot syndrome (HFS) among patients...