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Blood groups associated with risk of heart attack
PARIS—Having a blood type other than O is associated with a higher risk of heart attack, according to a meta-analysis. “It has been suggested...
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Drug receives orphan designation for AML
The US Food and Drug Administration (FDA) has granted orphan drug designation for PTX-200 for the treatment of acute myeloid leukemia (AML). PTX-...
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Simplifying consent forms doesn’t affect patient comprehension
Simplifying consent documents does not affect how well potential participants understand a clinical trial, according to new research. The study...
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FDA approves midostaurin to treat FLT3+ AML, advanced SM
The US Food and Drug Administration (FDA) has granted approval for the oral, multi-targeted kinase inhibitor midostaurin (Rydapt). The drug is...
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FDA approves test to detect FLT3 mutations
The US Food and Drug Administration (FDA) has approved use of the LeukoStrat® CDx FLT3 Mutation Assay as a companion diagnostic test. The...
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Pembrolizumab could change treatment paradigm, team says
The anti-PD-1 therapy pembrolizumab could change the treatment paradigm of relapsed or refractory classic Hodgkin lymphoma (cHL), according to...
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EC expands approval for daratumumab in MM
The European Commission (EC) has expanded the approved use of the anti-CD38 antibody daratumumab (Darzalex®). Daratumumab is now approved for use...
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Scientists create online database to aid CML research
A newly launched online database provides researchers with access to data on gene expression in chronic myeloid leukemia (CML). The LEUKomics...
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England did not benefit from CDF, analysis suggests
The National Health Service’s (NHS) Cancer Drugs Fund (CDF) has not benefitted the people of England and may have been detrimental for English...
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EMA recommends orphan status for drug for DLBCL
The European Medicines Agency (EMA) has recommended that PQR309 receive orphan drug designation for the treatment of patients with diffuse large B...
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How choline increases the risk of thrombotic events
Past research indicated that choline, a nutrient found in animal products, is associated with a heightened risk of thrombosis. Now, researchers...
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Fertility treatments linked to risk of pediatric cancers
Children born to mothers who underwent fertility treatments have an increased risk of developing pediatric neoplasms, according to research...
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TXA lowers risk of death from post-partum hemorrhage
Treatment with tranexamic acid (TXA) should become the frontline response to major bleeding after childbirth, according to researchers. Results...
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Program allows select Europeans access to belinostat
A managed access program is making the histone deacetylase inhibitor belinostat (Beleodaq®) available to patients in Europe who have relapsed or...
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DLA tablets cure drug-resistant malaria
Researchers have reported that tablets made from dried leaves of the Artemisia annua plant were able to cure malaria in 18 critically ill patients...