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How stress controls hemoglobin levels in blood
Researchers say they have discovered a new mechanism through which globin genes are expressed. Their discovery, described in Cell Research,...
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Disease burden impacts outcome of CAR T-cell therapy in B-ALL
WASHINGTON, DC—Results of a retrospective study suggest pretreatment disease burden impacts the outcome of chimeric antigen receptor (CAR) T-cell...
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FDA clears direct-to-consumer marketing of genetic risk tests
The US Food and Drug Administration (FDA) has authorized marketing of 23andMe Personal Genome Service (PGS) Genetic Health Risk (GHR) tests for 10...
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EC publishes guides on patient blood management
The European Commission (EC) has published guides intended to help hospitals and national authorities implement patient blood management (PBM)...
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Drug may be new option for difficult-to-treat DLBCL, doc says
WASHINGTON, DC—Selinexor has demonstrated the potential to become a new oral treatment option for patients with difficult-to-treat diffuse large B...
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Extremely short and long telomeres linked to risk of leukemia
WASHINGTON, DC—Telomere length may predict cancer risk and could be a target for future therapies, according to research presented at the AACR...
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Method may help MM patients avoid bone marrow biopsies
Engineers say they have devised a microfluidic technique to capture and count circulating plasma cells from small samples of blood. They believe...
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FDA approves drugs more quickly than EMA
The US Food and Drug Administration (FDA) reviews and approves new medicines in a shorter timeframe than the European Medicines Agency (EMA),...
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Inhibitor produces durable responses in rel/ref iNHL
WASHINGTON, DC—An investigational drug can produce durable responses and has a manageable safety profile in patients with relapsed or refractory...
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First fossilized mammalian RBCs, Babesia-type pathogens found
An amber specimen found in the Dominican Republic contained the first fossilized mammalian red blood cells (RBCs) and intraerythrocytic...
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Rule identifies women at low risk of VTE recurrence
Results of the REVERSE-II study appear to validate the utility of the HERDOO2 rule to identify women who can safely stop taking anticoagulants...
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Half of patients retain response to CAR T-cell therapy
WASHINGTON, DC—Roughly half of patients who responded to chimeric antigen receptor (CAR) T-cell therapy in the ZUMA-1 trial have retained that...
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Study provides new insight into RBC resilience
Researchers say they have developed a new system for studying the resilience of red blood cells (RBCs). The team’s microfluidic system allowed...
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New BTK inhibitor may overcome resistance in CLL
WASHINGTON, DC—Preclinical research suggests a second-generation BTK inhibitor may overcome the acquired resistance observed with its predecessor...
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ASCO addresses needs of SGMs with cancer
The American Society of Clinical Oncology (ASCO) has issued recommendations addressing the needs of sexual and gender minority (SGM) populations...