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JAK3 inhibitors could treat NK/T-cell lymphoma
Agents that inhibit the protein kinase JAK3 could prove effective for treating natural killer/T-cell lymphoma (NKTL), according to research...
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Antimalarials, antifungals may fight leukemia
A new study has shed light on the process leukemia cells use to evade apoptosis and revealed drugs that can fight this process. Investigators...
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Drug may be curative for certain HL patients
Photo from Business Wire Five-year follow-up data from a phase 2 trial indicate that a subset of Hodgkin lymphoma (HL) patients who fail...
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Guidelines cut costs, reduce waste of donated blood
Photo courtesy of UAB Hospital SAN DIEGO—Blood management guidelines can save millions of dollars and drastically reduce the waste of donated...
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Study challenges previous notions about RBC disposal
A new study contradicts previous beliefs about how the body disposes of red blood cells (RBCs) and recycles their iron. The work suggests the...
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Combo doesn’t improve PFS in DLBCL
Results of a phase 3 study suggest that obinutuzumab may not confer a benefit over standard therapy in patients with previously untreated diffuse...
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Compounds can kill multidrug-resistant lymphoma cells
Image courtesy of PNAS A class of newly discovered compounds can kill multidrug-resistant lymphoma cells by blocking the cells’ defenses against...
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Potential target for enhancing cancer immunotherapy
micrograph of a T cell Image from NIAID The “asymmetric division” of T cells could provide new ways to enhance cancer immunotherapy, according to...
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Automated cell counter approved for use in US
The US Food and Drug Administration has granted 510(k) clearance for the GloCyte Automated Cell Counter System and GloCyte Low and High Level...
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EC approves lenalidomide for rel/ref MCL
The European Commission (EC) has approved lenalidomide (Revlimid®) for the treatment of adults with relapsed or refractory mantle cell lymphoma (...
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Switch may increase supply of HSCs from cord blood
Photo courtesy of NHS Researchers have discovered a genetic switch that could increase the supply of hematopoietic stem cells (HSCs) derived from...
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Predicting outcomes in AML patients
Photo by Darren Baker An international competition has produced models that can help predict outcomes in patients with acute myeloid leukemia (...
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Weight loss lowers levels of cancer-associated proteins
A study of more than 400 women suggests that losing weight can reduce levels of cancer-promoting proteins in the blood. Overweight or obese women...
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Cancer patients and docs disagree about prognosis
patient and her father Photo by Rhoda Baer In a survey of advanced cancer patients and their oncologists, differing opinions about prognosis were...
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Study reveals increase in susceptibility to malaria
Photo by Gabrielle Tenenbaum Progress in reducing the malaria burden in Africa may have had the paradoxical effect of increasing malaria...