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Cancer cell lines predict drug response, study shows
Image from PNAS A study published in Cell has shown that patient-derived cancer cell lines harbor most of the same genetic changes found in...
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Mutations may be a ‘missing link’ in AML
Research published in Nature Communications suggests that mutations in the ZBTB7A gene are associated with t(8;21)-rearranged acute myeloid...
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Material can dissolve blood clots more efficiently, team says
Image by Kevin MacKenzie Researchers say they have developed a thrombolytic material that can be condensed on a blood clot by means of a magnetic...
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NICE recommends approval for bosutinib
Photo courtesy of CDC The National Institute for Health and Care Excellence (NICE) has issued a final draft guidance recommending approval for...
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NHL patients may have higher risk of second cancer
Photo courtesy of NIH Compared to patients with other common cancers, patients with non-Hodgkin lymphoma (NHL) have a higher risk of developing a...
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Results support INR self-monitoring/management
Results of a systematic review support self-monitoring and self-management for patients on long-term oral anticoagulation therapy. Researchers...
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Study reveals global variations of P vivax
from patients in Thailand Image by Wanlapa Roobsoong Researchers say they have uncovered the global, evolving, and historic make-up of the...
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EC extends marketing authorization for brentuximab vedotin
Photo from Business Wire The European Commission (EC) has extended the current conditional marketing authorization of brentuximab vedotin (...
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Drugs produce comparable results in CP-CML
Long-term results from the DASISION trial suggest that dasatinib and imatinib produce similar outcomes in patients with newly diagnosed chronic...
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EC expands approved use of carfilzomib
Photo from Amgen The European Commission (EC) has expanded the approved use of the proteasome inhibitor carfilzomib (Kyprolis). The drug is now...
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How multiple infections make malaria worse
Image by Ute Frevert and Margaret Shear New research suggests that infections with 2 types of malaria parasite lead to greater health risks...
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Study explains link between malignant hyperthermia and bleeding abnormalities
A new study helps explain why some patients with malignant hyperthermia may suffer from excessive bleeding. The findings suggest a mutation that...
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Team identifies potential therapeutic target for AML
New research suggests that E proteins and their antagonists, Id proteins, can play key roles in acute myeloid leukemia (AML). The study showed...
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Study reveals SNPs that may increase risk of MM
A large study has revealed several genetic variations that may increase a person’s risk of developing multiple myeloma (MM). The findings,...
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Efficacy of malaria vaccine declines over time
Photo by Caitlin Kleiboer Results from a phase 2 study of the malaria vaccine RTS,S (also known as RTS,S/AS01 or Mosquirix) suggest its efficacy...