News
Past donor pregnancy, sex do not affect transfusion-related mortality
- Author:
- Caleb Rans
A retrospective analysis of more than 1 million red blood cell transfusion recipients found that there was no significant increase in mortality...
News
ASCO clinical practice guideline update incorporates Oncotype DX
- Author:
- Caleb Rans
In women with hormone receptor–positive, axillary node–negative breast cancer with Oncotype DX recurrence scores of less than 26, there is minimal...
News
NCCN publishes pediatric ALL guidelines
- Author:
- Caleb Rans
While treatment for ALL often includes long-term chemotherapy regimens, various types of immunotherapy and targeted therapy are also summarized in...
News
Cediranib may alter DNA repair capacity
- Author:
- Caleb Rans
The preclinical finding may have implications for the development of combination treatment with olaparib for cancer patients.
News
Novel anti-PD-1 antibody can be given subcutaneously
- Author:
- Caleb Rans
“Subcutaneous administration of an anti-PD-1 antibody in patients with advanced solid tumors appears to be feasible,” the investigators wrote.
News
Revascularization plus exercise is most effective for intermittent claudication
- Author:
- Caleb Rans
Percutaneous transluminal angioplasty plus supervised treadmill exercise therapy could be a first-line treatment...
News
Genetic analysis identifies prognostic markers in CLL
- Author:
- Caleb Rans
A single 11q22 deletion, lacking an ATM mutation on the other allele, had the shortest progression-free survival among patients with CLL who were...
News
FVIII/W ratio may help predict relapse in hemophilia A
- Author:
- Caleb Rans
The biological marker was the first indication of relapse in most patients who relapsed during the study period.
News
Novel chromogenic assay looks accurate in hemophilia A diagnosis
- Author:
- Caleb Rans
The BIOPHEN FVIII:C assay had limited variation and performed well when compared with a one-stage clotting assay and another chromogenic assay,...
News
Low-dose FVIII prophylaxis reduced bleeding in hemophilia A
- Author:
- Caleb Rans
Low-dose prophylaxis with factor VIII outperformed on-demand treatment in children with severe hemophilia A. The findings have implications for...
News
Family history plays a large role in bleeding disorder diagnosis in women
- Author:
- Caleb Rans
The survey of women with congenital bleeding disorders in Europe highlighted delays in diagnosis and burdens on activities of daily living.
News
CD23 expression linked to improved survival in MCL
- Author:
- Caleb Rans
Researchers found that mantle cell lymphoma cases that were CD23 positive had a higher frequency of leukemic nonnodal presentation and CD200...
News
Literature review shows inconsistent measurement of financial toxicity
- Author:
- Caleb Rans
Systematic review reveals lack of validated instruments to effectively measure the financial burden experienced by cancer patients.
News
Younger patients with NSCLC tend to live longer
- Author:
- Caleb Rans
According to a retrospective analysis, younger patients with NSCLC had better survival, despite higher rates of brain metastasis and drive...
News
Most postapproval trials explore novel indications
- Author:
- Caleb Rans
Among 600 post-approval studies, only 12.0% solely examined the original therapeutic indication.