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FXIII replacement may improve hemostasis in acquired hemophilia A
The researchers found that measuring Factor XIII levels was useful in helping control hemostasis.
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Von Willebrand disease screening is low prior to hysterectomy
The level of screening – less than 1% – is out of alignment with current recommendations that call for consideration of underlying bleeding...
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Endoscopic full-thickness resection shows promise in CRC
After analysis, the investigators reported a technical success rate of 92.3% in patients who underwent the procedure.
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Novel biomarker could predict resistance to palbociclib
Several biomarkers were linked with the efficacy of palbociclib plus fulvestrant in patients with hormone receptor–positive, metastatic breast...
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Researchers characterize novel subtype of endocervical adenocarcinoma
Gastric-type mucinous carcinoma is a distinct variant of endocervical mucinous adenocarcinoma significantly associated with poor clinical outcomes...
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CLL, GVHD may raise risk for skin cancer after allo-HCT
The retrospective analysis identifies previously unknown risk factor for skin cancer associated with allogeneic hematopoietic cell transplantation...
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Model shows nivolumab plus ipilimumab cost effective in mRCC
A subgroup analysis indicated that nivolumab plus ipilimumab was most cost effective for patients with 1% or greater PD-L1 expression.
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Meta-analysis: Combo therapies best for neuroendocrine tumors
Also, various monotherapies outperform placebo, including everolimus, interferon, and sunitinib in pNETs; and somatostatin analogues in pNETs.
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Small study identifies skin microbiome changes after UV exposure
Bacterial composition of the skin biome was altered 24 hours post UVR exposure both within and between study subjects.
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Novel FVIII biomarker could help tailor hemophilia treatment
Patient-specific half maximal factor VIII effective concentrations measured using thromboelastography could help design a prophylaxis regimen.
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Ibrutinib-MTX-rituximab combo shows promise in CNS lymphoma
The researchers proposed an 840-mg dose of ibrutinib in future studies.
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TNF inhibitors improve BMD in ankylosing spondylitis
But the treatment did not improve vertebral fracture outcomes or radiographic progression.
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Clinical relevance of tamoxifen pharmacogenetics in question
Investigators found no significant association between endoxifen concentrations or CYP2D6 genotyping and relapse-free survival in patients with...
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Perceptions of liver transplantation for ALD are evolving
Liver transplantation for alcohol-associated liver disease is occurring earlier and more frequently than before.
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New guidance: Preventing steroid-induced osteoporosis in ITP
The British Society for Haematology offers recommendations on the use of glucocorticoids in the treatment of immune thrombocytopenia.