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VIDEO: Gluten-free diet tied to heavy metal bioaccumulation
Blood levels of mercury, lead, and cadmium were significantly higher in those who followed a gluten-free diet.
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Study eyed natural history of branch-duct intraductal papillary mucinous neoplasms
Most of these cysts were “indolent and dormant,” but some grew rapidly and developed “other worrisome features.”
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One in five Crohn’s disease patients have major complications after infliximab withdrawal
In a study of 102 patients, one in five with remitted Crohn’s disease developed a major complication after withdrawing from infliximab.
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Eradicating HCV significantly improved liver stiffness in meta-analysis
Liver stiffness decreased after patients achieved sustained virologic response.
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How to manage cytokine release syndrome
ATLANTA – Don’t wait to give anticytokine therapy.
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Daratumumab looks good in light chain amyloidosis
Preliminary data suggest a rapid hematologic response after one dose of daratumumab and high rates of response at 3 and 6 months.
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Survival improvements lag for young Hispanic patients with myeloma
For young Hispanic patients with myeloma, 5-year survival improved from 39% before 1996 to 56% from 2002 onward, a insignificant difference.
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Single-agent daratumumab active in smoldering multiple myeloma
ATLANTA – Daratumumab monotherapy led to durable partial responses among intermediate to high-risk patients with smoldering multiple myeloma.
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Study identifies predictors of acquired von Willebrand disease
ATLANTA – Successfully treating Waldenström macroglobulinemia often resolves acquired von Willebrand disease.
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HERCULES: Caplacizumab improved platelet response in aTTP
ATLANTA - Caplacizumab led to significantly faster platelet normalization and lower recurrence rates in acquired thrombotic thrombocytopenic...
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VIDEO: Caplacizumab sped platelet response, improved clinical outcomes in acquired TTP
ATLANTA – Phase 2 data on aTTP earned caplacizumab an FDA fast track designation in July 2017.
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Edoxaban noninferior to dalteparin for cancer-associated VTE
ATLANTA – Twelve months of daily edoxaban was noninferior to subcutaneous therapy with dalteparin for VTE in patients with cancer.
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Study supports methotrexate monotherapy with TNF inhibitor rescue for early RA treatment
Findings suggest that a stepwise treat-to-target strategy can prevent overtreatment in about one in four patients with early RA.
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Three-month response to CAR T-cells looks durable in DLBCL
ATLANTA – A quarter of the patients in the study were infused as outpatients.
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MAVORIC: Mogamulizumab tops vorinostat in pretreated CTCL
ATLANTA – Mogamulizumab topped vorinostat in terms of overall response to treatment and on several quality of life scales