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Barzolvolimab Effective for CSU in Phase 2 Study
Barzolvolimab is an anti-KIT monoclonal antibody that inhibits the activation of and depletes mast cells.
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Children With Severe Atopic Dermatitis Catch Up on Growth With Dupilumab
Children at the lower percentiles of height receiving prompt treatment with dupilumab “were able to rapidly move through the centiles over the 16...
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Nemolizumab Benefits for Atopic Dermatitis Maintained in Long-Term Follow-Up Study
Nemolizumab was associated with “ongoing clinically meaningful improvements in itch, skin lesions, and sleep disturbance,” reported Dr. Diamant...
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Lichen Planus Responds to Treatment with Topical Ruxolitinib in Phase 2 Study
Ruxolitinib cream twice daily resulted in “significant improvements in cutaneous lichen planus disease severity vs vehicle” after 16 weeks of...
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Effects of Bimekizumab Durable for HS Through One Year
“Efficacy and health-related quality-of-life outcomes were maintained through 2 years of treatment,” according to the study presenter.
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Many Hurdles Exist to Treating Lung Cancer With CAR T Cells
Unleashing the immune system in a highly specific manner, ‘is obviously, in a way, a holy grail’ in lung cancer, said an expert at the W...
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NCCRT Confirmed as Best Approach in Locally Advanced, Resectable ESCC
Researchers compred neoadjuvant concurrent chemoradiotherapy with adjuvant sequential chemoradiotherapy (ASCRT) in locally advanced esophageal...
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Melanoma: Neoadjuvant Immunotherapy Provides Optimal Survival Results
Those who received combination therapy achieved higher event- and recurrence-free survival than patients who received monotherapy.
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Which Patients With Early TNBC Can Avoid Chemotherapy?
Researchers examine breast cancer–specific survival at prespecified stromal TIL cutoffs in women with stage I TNBC who had undergone a lumpectomy...
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Does An Elevated Lp(a) Call for Low-dose Aspirin?
Guidelines suggest testing for proinflammatory Lp(a), but questions remain and testing access is scarce.
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Does Semaglutide Reduce Inflammation?
Study finds an association between semaglutide and reduced inflammatory marker levels; implications are yet unknown.
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Novel PCSK9 Drives High-Risk Patients to Target LDL
Lerodalcibep leads to “substantial additional LDL cholesterol reductions on top of existing oral agents.”
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Experts Focus on Quality-of-Life Data in Prostate Cancer
Trials presented at ASCO explore the effects of treatment suspension or intensification on health-related QoL and interventions to manage side...
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Delays After Tests for Suspected Heart Failure ‘a Scandal’
Despite eight times greater hospitalization rates, and suspected heart failure in two thirds, fewer than 30% of patients received a diagnosis in a...
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Yoga May Augment Medical Therapy in Heart Failure
Yoga was beneficial for heart failure patients on optimal medical management, showing an overall improvement in left ventricular size and function...