Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Evidence Builds for Effects of Obesity, Low Physical Activity on Development of Psoriatic Arthritis

Publish date:: December 12, 2019

Key clinical point: High BMI, high waist circumference, and lower levels of physical activity all increase the risk of developing psoriatic arthritis.

Major finding: Obese individuals had an adjusted HR of 2.46 (95% CI, 1.65-3.68), compared with participants at normal weight.

Study details: A longitudinal, population-based study of data from 36,626 women and men without diagnosed PsA at baseline.

Disclosures: The study was partially funded by a grant the first author received from the Norwegian Extra Foundation for Health and Rehabilitation. The authors reported no conflicts of interest.

Citation:

Thomsen RS et al. Arthritis Care Res. 2019 Dec 7. doi: 10.1002/acr.24121.

This Week's Must Reads

Osteoporosis prevalence in PsA similar to general population,

Swedish registry study finds atopic dermatitis significantly associated with autoimmune diseases,

Weight loss may be paramount lifestyle change in preventing gout,

Gut microbiome influences response to methotrexate in new-onset RA patients,

Early treatment of RA with DMARDs promotes sustained remission,

Must Reads in Psoriatic Arthritis

Osteoporosis prevalence in PsA similar to general population,

Synovial, skin gene expression differences may explain PsA treatment responses,

Tildrakizumab for psoriasis shows durable efficacy over 5 years,

Non-Whites remain sorely underrepresented in phase 3 psoriasis trials,

Guselkumab improvements for psoriatic arthritis persist through 1 year,