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Adults with Cerebral Palsy and Fracture Risk Link
J Bone Miner Res; ePub 2019 Feb 7; Whitney, et al
Young and middle‐aged adults with cerebral palsy (CP) have an elevated prevalence of all‐cause fracture compared to adults without CP, which was present even after accounting for cardiometabolic diseases and osteoporosis, according to a recent study. Data were from a de‐identified nationwide claims database of beneficiaries from a single private payer. Beneficiaries aged 18-64 years with and without CP were identified, as well as any fracture, which consisted of osteoporotic pathological fracture and any type of fracture of the head/neck, thoracic, lumbar/pelvic, upper extremity, and lower extremity regions. The prevalence of any fracture was compared between adults with (n=5,555) and without (n=5.5 million) CP. Researchers found:
- Adults with CP had a higher prevalence of all‐cause fracture (6.3%, 2.7%, respectively) and fracture of the head/neck, thoracic, lumbar/pelvic, upper extremity, and lower extremity regions compared to adults without CP.
- After adjusting for sociodemographic and socioeconomic variables, adults with CP had higher odds of all‐cause fracture compared to adults without CP (OR=2.5).
- After further adjusting for cardiometabolic diseases, adults with CP had higher odds of all‐cause fracture compared to adults without CP (OR=2.2).
Whitney DG, Alford AI, Devlin MJ, Caird MS, Hurvitz EA, Peterson MD. Adults with cerebral palsy have higher prevalence of fracture compared to adults without cerebral palsy independent of osteoporosis and cardiometabolic diseases. [Published online ahead of print February 7, 2019]. J Bone Miner Res. doi:10.1002/jbmr.3694.