Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Knees with Chondrocalcinosis Linked with Pain

Arthritis Care Res; ePub 2017 Jan 27; Kwanghoon, et al

Knees with chondrocalcinosis had increased pain and did not have higher synovitis scores on MRI compared to knees without chondrocalcinosis, a recent study found. Data were obtained from the Osteoarthritis Initiative (OAI) public use data sets. Researchers examined the relationship between chondrocalcinosis on baseline knee radiograph and pain at baseline and at 4 years. They found:

  • Knees with chondrocalcinosis (n=162) more often had pain compared to knees without chondrocalcinosis (n=2,030) at baseline and had higher Western Ontario and McMaster Universities Arthritis Index (WOMAC) pain scores both at baseline (2.4 vs 1.8) and at 4 years (2.5 vs 1.6) as well as higher Intermittent and Constant Osteoarthritis Pain (ICOAP) intermittent pain scores at 4 years.
  • There was no difference in MRI Osteoarthritis Knee Score (MOAKS) synovitis scores at baseline and at 4 years between the chondrocalcinosis group (n=102) and the control group (n=99).

Citation:

Kwanghoon B, Kim W, Niu J, et al. Chondrocalcinosis in knee joints is associated with pain but not with synovitis: Data from the Osteoarthritis Initiative. [Published online ahead of print January 27, 2017]. Arthritis Care Res. doi:10.1002/acr.23208.