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Incident Gout in Sleep Apnea

Assessing the risk

Publish date:: October 26, 2015

Sleep apnea is independently associated with an increased risk of incident gout, according to a study of 9,865 patients with newly diagnosed sleep apnea and 43,598 comparators. Researchers found:

• 270 incident cases of gout were identified during 1 year of follow-up.

• Incidence of gout among patients with apnea was 8.4/1,000; among comparators incidence was 4.8/1,000.

• Crude and multivariate rate ratios of incident gout for sleep apnea were 1.7 and 1.5, respectively.

• Corresponding rate differences were 3.6 and 2.8 per 1,000 person/years.

• The effect of sleep apnea persisted across subgroups.

Citation: Zhang Y, Pelquin C, Dubreuil M, et al. Sleep apnea and the risk of incident gout: A population-based body mass index-matched cohort study. [Published online ahead of print October 19, 2015]. Arthritis Rheumatol. doi: 10.1002/art.39330.

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