Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

ACP Releases Guidelines on Gout Management

Ann Intern Med; 2017 Jan 3; Qaseem, Harris, et al

Publish date:: January 30, 2017

The American College of Physicians (ACP) has developed a guideline to present the evidence and provide clinical recommendations on the management of gout. Using the ACP grading system, the committee based these recommendations on a systematic review of randomized, controlled trials; systematic reviews; and large observational studies published between January 2010 and March 2016. Recommendations are as follows:

Clinicians should choose corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs), or colchicine to treat patients with acute gout.
Clinicians should use low-dose colchicine when using colchicine to treat acute gout.
ACP recommends against initiating long-term urate-lowering therapy in most patients after a first gout attack or in patients with infrequent attacks.
Clinicians should discuss benefits, harms, costs, and individual preferences with patients before initiating urate-lowering therapy, including concomitant prophylaxis, in patients with recurrent gout attacks.

Citation:

Qaseem A, Harris RP, Forciea MA; for the Clinical Guidelines Committee of the American College of Physicians. Management of acute and recurrent gout: A clinical practice guideline from the American College of Physicians. Ann Intern Med. 2017;166(1):58-68. doi:10.7326/M16-0570.

This Week's Must Reads

Osteoporosis prevalence in PsA similar to general population,

Swedish registry study finds atopic dermatitis significantly associated with autoimmune diseases,

Weight loss may be paramount lifestyle change in preventing gout,

Gut microbiome influences response to methotrexate in new-onset RA patients,

Early treatment of RA with DMARDs promotes sustained remission,

Must Reads in Clinical Guidelines

Medication Guideline for Patients Undergoing THA, TKA, Arthritis Rheumatol; ePub 2017 Jun 16; Goodman, et al

ACP Updates Guidelines for Osteoporosis, Ann Intern Med; ePub 2017 May 9; Qaseem, et al

Treatment Guidelines for Sjögren’s Syndrome, Arthritis Care Res; ePub 2017 Mar 3; Carsons, et al

ACP Releases Guidelines on Gout Management, Ann Intern Med; 2017 Jan 3; Qaseem, Harris, et al