Cases That Test Your Skills

Decompensation in a 51-year-old woman with schizophrenia

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Bottom Line

The menopausal transition is a time of increased risk for women with schizophrenia. For peri- and postmenopausal women with schizophrenia, a selective estrogen receptor modulator, such as raloxifene, may be considered as an adjunctive therapy. Evaluate the risks and benefits of raloxifene, particularly the increased risk of thromboembolism, before starting this medication.

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Drug Brand Names

Chlorpromazine Thorazine
Clozapine Clozaril
Fluphenazine Prolixin
Haloperidol Haldol
Paliperidone Invega
Quetiapine Seroquel
Raloxifene Evista
Ziprasidone Geodon

Acknowledgment

The authors thank the nurses at the VA Puget Sound Health Care System, Seattle, Washington.

Pages

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